Moshkowitz M, Toledano O, Galazan L, Hallak A, Arber N, Santo E. Incidence of colorectal neoplasms among male pilots. World J Gastroenterol. 2014 Jul 21;20(27):9116-20. PMID: 25083084.

World J Gastroenterol. 2014 Jul 21;20(27):9116-20. doi: 10.3748/wjg.v20.i27.9116.

Incidence of colorectal neoplasms among male pilots.

Moshkowitz M(1), Toledano O(1), Galazan L(1), Hallak A(1), Arber N(1), Santo E(1).

Author information:
(1)Menachem Moshkowitz, Ohad Toledafno, Lior Galazan, Aharon Hallak, Nadir Arber, Erwin Santo, Integrated Cancer Prevention Center and Department of Gastroenterology, Tel- Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel.

AIM: To assess the prevalence of colorectal neoplasms (adenomas, advanced adenomas and colorectal cancers) among Israeli military and commercial airline pilots.

METHODS: Initial screening colonoscopy was performed on average-risk (no symptoms and no family history) airline pilots at the Integrated Cancer Prevention Center (ICPC) in the Tel-Aviv Medical Center. Visualized polyps were excised and sent for pathological examination. Advanced adenoma was defined as a lesion >10 mm in diameter, with high-grade dysplasia or villous histology. The results were compared with those of an age- and gender-matched random sample of healthy adults undergoing routine screening at the ICPC.

RESULTS: There were 270 pilots (mean age 55.2 ± 7.4 years) and 1150 controls (mean age 55.7 ± 7.8 years). The prevalence of colorectal neoplasms was 15.9% among the pilots and 20.6% among the controls (P = 0.097, χ (2) test). There were significantly more hyperplastic polyps among pilots (15.5% vs 9.4%, P = 0.004) and a trend towards fewer adenomas (14.8% vs 20.3% P = 0.06). The prevalence of advanced lesions among pilots and control groups was 5.9% and 4.7%, respectively (P = 0.49), and the prevalence of cancer was 0.7% and 0.69%, respectively (P =0.93).

CONCLUSION: There tends to be a lower colorectal adenoma, advanced adenoma and cancer prevalence but a higher hyperplastic polyp prevalence among pilots than the general population.

PMCID: PMC4112875

PMID: 25083084  [PubMed - indexed for MEDLINE]

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