Moshkowitz M, Toledano O, Galazan L, Hallak A, Arber N, Santo E. Incidence of colorectal neoplasms among male pilots. World J Gastroenterol. 2014 Jul 21;20(27):9116-20. PMID: 25083084.
World J Gastroenterol. 2014 Jul 21;20(27):9116-20. doi: 10.3748/wjg.v20.i27.9116.
Incidence of colorectal neoplasms among male pilots.
Moshkowitz M(1), Toledano O(1), Galazan L(1), Hallak A(1), Arber N(1), Santo E(1).
AIM: To assess the prevalence of colorectal neoplasms (adenomas, advanced adenomas and colorectal cancers) among Israeli military and commercial airline pilots.
METHODS: Initial screening colonoscopy was performed on average-risk (no symptoms and no family history) airline pilots at the Integrated Cancer Prevention Center (ICPC) in the Tel-Aviv Medical Center. Visualized polyps were excised and sent for pathological examination. Advanced adenoma was defined as a lesion >10 mm in diameter, with high-grade dysplasia or villous histology. The results were compared with those of an age- and gender-matched random sample of healthy adults undergoing routine screening at the ICPC.
RESULTS: There were 270 pilots (mean age 55.2 ± 7.4 years) and 1150 controls (mean age 55.7 ± 7.8 years). The prevalence of colorectal neoplasms was 15.9% among the pilots and 20.6% among the controls (P = 0.097, χ (2) test). There were significantly more hyperplastic polyps among pilots (15.5% vs 9.4%, P = 0.004) and a trend towards fewer adenomas (14.8% vs 20.3% P = 0.06). The prevalence of advanced lesions among pilots and control groups was 5.9% and 4.7%, respectively (P = 0.49), and the prevalence of cancer was 0.7% and 0.69%, respectively (P =0.93).
CONCLUSION: There tends to be a lower colorectal adenoma, advanced adenoma and cancer prevalence but a higher hyperplastic polyp prevalence among pilots than the general population.
PMID: 25083084 [PubMed - indexed for MEDLINE]