Kalba DU, Golan S, Livne PM, Pode D, Duvdevani M, Lifshitz D. Urinary stone composition in Israel: current status and Variation with age and Gender-Abicenter study. J Endourol. 2013 Aug 30. [Epub ahead of print] PubMed PMID: 23987580.

J Endourol. 2013 Aug 30. [Epub ahead of print]

Urinary stone composition in Israel: current status and Variation with age and Gender-A bicenter study.

Kalba DU, Golan S, Livne PM, Pode D, Duvdevani M, Lifshitz D.

RABIN MEDICAL CENTER and SAKLER TEL AVIV UNIVERSITY SCHOOL OF MEDICINE, UROLOGY, PETAH TIKVAH, TEL AVIV, Israel ;
kalba_mc@yahoo.com.

Introduction The epidemiological data regarding stone composition in Israel is based on anachronistic methods of stone analysis. Historically, Israel was noted  for an unusually high percentage of uric acid stones. Purpose To describe the current stone composition distribution in Israel, utilizing modern techniques of  urinary stone analysis. Age and gender correlations were investigated.

Materials and Methods: In a bi-center study, using infrared spectroscopy and X-ray diffraction, stones from five hundred and fiffty eight (538) patients were analyzed and demographic data recorded. Results The study cohort included 401 men (74.5%) and 137 women (25.5%) with a male to female ratio of 2.9:1 and a median age of 48 years (range: 2-85 years). While calcium oxalate monohydrate was the predominant component in both genders it was lower in female patients (77.3% vs.65%). The rate of infection stones (struvite+carbonate apatite) was significantly higher in women (35.7% vs. 10.2%). Uric acid stone were found in only 14.5% of the patients and increased with age. Conversly the rate of COD decreased with age.

Conclusions: Modern techniques of urinary stone analysis showed that the most frequent stone component in Israel is Calcium oxalate Monohydrate. In contrast to earlier reports and in accordance with reports from other countries, the overall frequency of uric acid is 14.5%. With age the frequency of uric acid increases reaching 21% in people > 60 years old. A significant gender difference was noted in the distribution of Calcium Oxalate stones and infection stones. However the classic 3:1 ration was maintained.

PMID: 23987580  [PubMed - as supplied by publisher]

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